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National Institute on Drug Abuse (NIDA)

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Problem overview

All opioids are chemically related and interact with opioid receptors in nerve cells in the body and brain. Opioid pain relievers are generally safe when taken for short periods of time as prescribed by a doctor, but can be misused because they provide pain relief and euphoria (either when taken differently or when prescribed). overdose or without a doctor’s prescription). Regular use of opioid pain relievers, even as prescribed by a doctor, can lead to dependence, and misuse can lead to dependence, overdose, and death.

An opioid overdose can be reversed with immediate administration of the drug naloxone. Several parts of the country have seen improvements in the form of reduced availability of prescription opioid pain relievers and reduced misuse among her teenagers in the country. But since 2011, there has been a dramatic increase in heroin overdose deaths. Fortunately, there are effective drugs for treating opioid use disorders, such as methadone, buprenorphine, and naltrexone.

A NIDA study found that once treatment was initiated, both the buprenorphine/naloxone combination and the extended-release naltrexone formulation were equally effective in treating opioid addiction. It has been more difficult to initiate treatment among active users because it requires detoxification.These drugs help many recover from opioid addiction.



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